Reining in a runaway gene in neuroblastoma

06/04/2018


Our scientists have found a way to rein in a cancer-causing gene called MYCN and slow down the growth of the childhood cancer neuroblastoma.

'cells with the normal amount of the MYCN gene (left), and cells with multiple copies of MYCN (right)

It’s in the delivery: researchers find a new way to target neuroblastoma

12/03/2018


Our researchers have used a tiny drug delivery vehicle to kill neuroblastoma cells without harming normal tissues.

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How specific DNA ‘microdeletions’ help predict leukaemia relapse

11/12/2017


If doctors can reliably tell which children are most likely to get their leukaemia back, they can offer more intensive treatment options to prevent it.

'Associate Professor Rosemary Sutton

How we’re stopping neuroblastoma’s blood supply in its tracks

11/08/2017


Blood vessels supply the fuel needed for rapid tumour growth and spread. But what happens when the network is disrupted?

'Dr Orazio Vittorio discusses his research with SBS journalist Michelle Rimmer

Sights set on an aggressive childhood leukaemia

17/07/2017


Our latest research is providing ammunition to target the rare but aggressive MLLr leukaemia subtype.

'Mother holding a baby's hand during treatment

Childhood cancers defy current understanding

21/06/2017


A surprising discovery transforms our thinking about one of the ‘universal features’ of cancer.

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New leukaemia subtype found by DNA test

31/03/2017


A previously unknown subgroup of high-risk leukaemia in children has been revealed with a new, more accurate DNA test.

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Joining the dots to find neuroblastoma drug target

16/03/2017


By looking at DNA-packing proteins, we identified a new drug target for neuroblastoma called DOT1L. See how we joined the dots.

'96-well plate in lab for testing

Glowing report: firefly gene shows hidden leukaemia cells

16/02/2017


A test that makes drug-resistant leukaemia cells glow could reveal a brighter future for developing new leukaemia therapies.

'Dr Luke Jones with bioluminescent images

Targeting high-risk leukaemia subtypes

27/09/2016


A study published this month shows venetoclax could successfully target high-risk leukaemia subtypes in infants or children. Clinical trials are planned.

'Blood cells from leukaemia patient