New gene found in neuroblastoma offers possibility of targeted treatment

31/07/2019


Our researchers have discovered that a gene called JMJD6 plays an important role in the most aggressive form of neuroblastoma. What’s more, they’ve developed a targeted treatment against it.

'

Anticancer drug CBL0137 is highly effective against the most common type of infant leukaemia

28/07/2019


Findings just published by our researchers reveal that anticancer drug CBL0137, previously shown to be active against many different cancers, is also highly effective against MLL-rearranged leukaemia, including the most common type of infant leukaemia.

'

Therapy developed for Alzheimer’s Disease could offer hope to leukaemia patients

30/05/2019


In research published this week, scientists have found that a therapy originally developed to treat Alzheimer’s Disease could hold promise for children with T-cell acute lymphoblastic leukaemia.

'

Our researchers combine an old drug with a new one to starve neuroblastoma

18/02/2019


Our researchers have found a way to dramatically slow neuroblastoma growth, using a combination of drugs that starves cells of essential nutrients called polyamines.

'

Fundamental mechanism behind chemotherapy resistance revealed

17/12/2018


Groundbreaking research from our Leukaemia Biology Program has revealed how acute lymphoblastic leukaemia can become resistant to a class of anti-cancer drugs called glucocorticoids.

'

New imaging method could help treat and monitor neuroblastoma

19/11/2018


Our researchers have developed a method to measure the amount of copper inside neuroblastoma tumours. Published in the journal Theranostics, it offers a potential tool for treating and monitoring neuroblastoma.

'

Tracking cancer with gold-coated nanoparticles

30/08/2018


Research published this week shows that gold-coated nanoparticles can be used to detect tiny amounts of cancer-related molecules in blood.

'

Reining in a runaway gene in neuroblastoma

06/04/2018


Our scientists have found a way to rein in a cancer-causing gene called MYCN and slow down the growth of the childhood cancer neuroblastoma.

'cells with the normal amount of the MYCN gene (left), and cells with multiple copies of MYCN (right)

It’s in the delivery: researchers find a new way to target neuroblastoma

12/03/2018


Our researchers have used a tiny drug delivery vehicle to kill neuroblastoma cells without harming normal tissues.

'

How specific DNA ‘microdeletions’ help predict leukaemia relapse

11/12/2017


If doctors can reliably tell which children are most likely to get their leukaemia back, they can offer more intensive treatment options to prevent it.

'Associate Professor Rosemary Sutton