A/Prof Joshua McCarroll
BSc (Hons), PhD (UNSW);
A/Prof McCarroll is a Team Leader in the Tumour Biology and Targeting Program at the Children’s Cancer Institute and the Australian Centre for NanoMedicine, UNSW.
A/Prof McCarroll completed his PhD in 2005 at UNSW and joined the University of Massachusetts Medical School, USA for post-doctoral studies (2005-07). During this time he gained experience in using cutting-edge technologies to develop RNA interference (RNAi) agents and nanotechnology as therapeutics to treat human disease.
Since joining Children’s Cancer Institute in 2007, the focus of A/Prof McCarroll's research has been to develop therapies which increase the efficiency of chemotherapy drugs while reducing toxic side-effects to normal cells. His research interests include:
• identifying new drug targets using RNAi in childhood (neuroblastoma, brain cancer) and adult (lung, pancreatic) cancers.
• designing nanomaterials which can encapsulate high amounts of therapeutic drugs and deliver them to cancer cells.
• examining the therapeutic potential of novel nanomedicines in preclinical in vitro and in vivo cancer models.
Potential honours and PhD projects in his lab include:
• developing nanotechnology for the treatment of childhood brain cancer
• identifying new therapeutic gene targets using RNAi library screens to inhibit lung cancer growth.
A/Prof McCarroll is a conjoint senior lecturer in the Medicine faculty at UNSW.