Clinical Translation

Head of Theme

The Clinical Translation Theme is a critical part of the Institute's overarching goal to bring fundamental discoveries to the clinic.  We are translating cancer breakthroughs by harnessing the power of people and technology to reshape the future for children with cancer and their families?.

Our?Theme includes research initiatives that focus on clinical application. This involves harnessing emerging technologies and novel data-driven approaches to develop and implement novel methods for diagnosis, risk-stratification, disease monitoring, and advanced precision medicine interventions. We also support the development and delivery of novel studies and clinical trials that enable the translation of these new methods into routine clinical care. 

Our broad aims are to utilise innovative technology and data analytics, and support the translation of novel discoveries and practices into the clinic to achieve tangible health benefits for children. 

We are a diverse and multi-disciplinary team encompassing wet- and dry-lab genomic oncology researchers and clinicians. We have expertise in pre-clinical high-throughput drug screening on patient samples, implementing novel technologies to assess circulating tumour cells and DNA using non-invasive liquid biopsy approaches to monitor disease more effectively, exploring the immune microenvironment using novel spatial technologies, integrating and analysing multi-omic data on patient samples within a clinically relevant timeframe, and evaluating the clinical, psychosocial, legal, and ethical impact of these discoveries.  

Our approaches allow us to understand how we can better identify, detect, diagnose, monitor, risk stratify and support children with cancer and their families, and develop new studies to bring cutting edge scientific discoveries rapidly into the clinic.    

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