About childhood cancer

Worldwide, about 400,000 new cases of cancer are diagnosed each year in children and adolescents.

Cancer kills three children every week in Australia – more than any other disease.

70% of children who survive cancer suffer long-term effects from their treatment.

What is childhood cancer?

Childhood cancer is not simply adult cancer in a child. Cancers in children are often different in their causes, the way they grow and spread, and how they respond to treatment.

When a child is diagnosed with cancer there is usually no known cause. This makes it very hard for parents, who are left with unanswered questions about why their child has cancer, and if there was anything they could have done to prevent it.

The lives of their entire family are thrown upside-down. Treatment can go for years, can be very intensive and expensive, and puts an enormous strain on family life. When a child dies, an average of 70 potential years of life are lost.1

Of those who do survive, two-thirds will have significant long-term treatment side effects, including organ dysfunction, neurocognitive deficits, impaired fertility, and secondary malignancies.

In Australia, more than 1000 children and adolescents are diagnosed with cancer each year.

When a child dies from cancer, an average 70 potential years of life are lost.

The overall survival rate for childhood cancer has now risen to over 80%, thanks to medical research.

The challenge of childhood cancer

Childhood cancer poses two major challenges. First: for every ten children diagnosed with cancer, two don’t survive. And second: most children who survive cancer go on to suffer long-term (sometimes life-long) health issues as a result of their treatment.

Many people are surprised to learn that almost all cancer treatments used in children today were actually developed for adults. Most of these treatments (such as chemotherapy or radiotherapy) target all rapidly growing cells (not just cancer cells), and this leads to harsh side-effects, especially in young, growing bodies.

While the overall survival rate for childhood cancer is now over 80%, for some types of cancer the rate is much lower. In fact, there are some childhood cancers for which there are no treatments and which are uniformly fatal. The need for more effective and safer treatments for children is urgent.

What cancers do children get?

There are many different types of cancer that children can get. Some of the most common childhood cancers are listed below.

  • Leukaemia - this is cancer of the blood and bone marrow, and is the most common childhood cancer.
  • Brain cancer - this is cancer that grows in the brain, and is the second most common childhood cancer. It kills more children than any other type of cancer.
  • Neuroblastoma - the most common solid tumour diagnosed in children under 5 years.
  • Sarcoma - a cancer that grows in the bones and connective tissues of the body.
  • Lymphoma - cancer that develops in the lymphatic system.
  • Seeking a Cure for DIPG - aggressive form of brain tumor that primarily affects children in the pons, a critical area of the brainstem, making it extremely challenging to treat.

Key facts

  • Worldwide, about 400,000 new cases of cancer are diagnosed each year in children and adolescents.
  • In Australia, more than 1000 children and adolescents are diagnosed with cancer each year.
  • When a child dies from cancer, an average 70 potential years of life are lost.
  • Cancer kills more children than any other disease in Australia.
  • About three children and adolescents per week die from cancer in Australia.
  • Two-thirds of children who survive cancer suffer serious long-term effects.
  • The overall survival rate for childhood cancer has now risen to over 80%, thanks to medical research.

Sources

Cancer Australia: https://childrenscancer.canceraustralia.gov.au/about-childrens-cancer/statistics 

Australian Institute of Health and Welfare: https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia 

Australian Childhood Cancer Registry: https://cancerqld.blob.core.windows.net/content/docs/Childhood-Cancer-in-Australia-1983-2015.pdf 

Medical Journal of Australia 2020; 212: 110-111 

Journal of the National Cancer Institute 2001; 93: 341 

Lancet Oncol 2017; 18: 719–31 

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